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Creatine in mouse models of neurodegeneration and aging

โœ Scribed by T. Klopstock; M. Elstner; A. Bender


Book ID
106222331
Publisher
Springer
Year
2011
Tongue
English
Weight
183 KB
Volume
40
Category
Article
ISSN
0939-4451

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## Abstract A critical role of mitochondrial dysfunction and oxidative damage has been hypothesized in both aging and neurodegenerative diseases. Much of the evidence has been correlative, but recent evidence has shown that the accumulation of mitochondrial DNA mutations accelerates normal aging, l