DNA methylation of human class II genes of the Major Histocompatibility Complex (MHC) was correlated with gene expression and methyl-related CG --~ TG and CG --+ CA changes. It was found Uhat cytosine methylation of the CG dinucleotides of MHC class II genes should be involved in generating a fracti
✦ LIBER ✦
CpG dinucleotides are mutation hot spots in phenylketonuria
✍ Scribed by Abadie, Véronique; Lyonnet, Stanislas; Maurin, Nicole; Berthelon, Monique; Caillaud, Catherine; Giraud, Francis; Mattei, Jean-François; Rey, Jean; Rey, Françoise; Munnich, Arnold
- Book ID
- 122465026
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 450 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0888-7543
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## Communicated by Marc Greenblatt An analysis of mutations was performed in 141 Duchenne muscular dystrophy (DMD) patients previously found to be negative for large deletions by standard multiplex PCR assays. Comprehensive mutation scanning of all coding exons, adjacent intronic splice regions, a