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Cover Picture: The Effect of High Pressure on the Heck Reaction − A Contribution to a Deeper Understanding of the Mechanism (Eur. J. Org. Chem. 13/2003)

✍ Scribed by Michael Buback; Thomas Perković; Stefan Redlich; Armin de Meijere

Publisher: John Wiley and Sons
Year: 2003
Tongue: English
Weight: 67 KB
Volume: 2003
Category: Article
ISSN: 1434-193X
DOI: 10.1002/ejoc.200390228

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✦ Synopsis

Abstract

The cover picture shows the influence of high pressure on the Heck cross‐coupling reaction. As reflected by its generally accepted mechanism, this palladium‐catalyzed reaction proceeds in a number of distinctly different steps, some of which ought to be retarded by high pressure. Yet, the overall effect leads to a significant acceleration, and the reaction has a negative volume of activation. The kinetic parameters were determined by monitoring the reaction in a massive metal cylinder − as seen in the background − by on‐line FT‐IR spectroscopy. Details are discussed in the article by A. de Meijere et al. on p. 2375 ff.

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