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Cover Picture: Molecular Design and Chemical Synthesis of a Highly Potent Epothilone (ChemMedChem 1/2006)

✍ Scribed by K. C. Nicolaou; Benjamin A. Pratt; Stellios Arseniyadis; Markus Wartmann; Aurora O'Brate; Paraskevi Giannakakou


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
45 KB
Volume
1
Category
Article
ISSN
1860-7179

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Cover Picture: Modulators of the Kynuren
✍ Roberto Pellicciari; Rosa C. Rizzo; Gabriele Costantino; Maura Marinozzi; Laura 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 58 KB

**The cover picture shows** one branch of the kynurenine pathway of tryptophan metabolism, which is mainly localized in astrocytes. One key metabolite, kynurenic acid (KYNA), is transported in the extracellular space, where it modulates synaptically localized α7 nicotinic acetylcholine receptors and