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Cover Picture: Mass Spectrometric Profiling of Intact Biological Tissue by Using Desorption Electrospray Ionization (Angew. Chem. Int. Ed. 43/2005)

✍ Scribed by Justin M. Wiseman; Satu M. Puolitaival; Zoltán Takáts; R. Graham Cooks; Richard M. Caprioli

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
67 KB
Volume
44
Category
Article
ISSN
0044-8249

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✦ Synopsis

Desorption electrospray ionization is applied to the mass spectrometric profiling of phospholipids. In their Communication on page 7094 ff., R. G. Cooks, R. M. Caprioli, and co‐workers report the rapid analysis of untreated biological tissues, including the tumor region of liver tissue. The impact of charged liquid microdroplets on liver tissue in air and the release of lipids and other molecules as ions for analysis is illustrated in the cover picture (prepared by Z. Ouyang, J. Wiseman, and R. Shreve).

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Titelbild: Mass Spectrometric Profiling
Titelbild: Mass Spectrometric Profiling of Intact Biological Tissue by Using Desorption Electrospray Ionization (Angew. Chem. 43/2005)
✍ Justin M. Wiseman; Satu M. Puolitaival; Zoltán Takáts; R. Graham Cooks; Richard 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 68 KB 👁 1 views

**Die Desorptions‐Elektrospray‐Ionisierung** wird für die massenspektrometrische Analyse von Phospholipiden genutzt. In ihrer Zuschrift auf S. 7256 ff. beschreiben R. G. Cooks, R. M. Caprioli et al. die schnelle Analyse von unbehandelten biologischen Geweben, darunter der Tumorregion von Lebergewebe

Mass Spectrometric Profiling of Intact B
Mass Spectrometric Profiling of Intact Biological Tissue by Using Desorption Electrospray Ionization
✍ Justin M. Wiseman; Satu M. Puolitaival; Zoltán Takáts; R. Graham Cooks; Richard 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 138 KB

Imaging mass spectrometry has emerged as a powerful technique based on time-of-flight secondary-ion mass spectrometry (TOF-SIMS) [1] and matrix-assisted laser desorption/ ionization (MALDI). [2,3] However, until now, the massspectrometric analysis of biological tissues has been limited to techniques