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Covalent adduction of nucleophilic amino acids by 4-hydroxynonenal and 4-oxononenal

✍ Scribed by Jonathan A Doorn; Dennis R Petersen


Book ID
114008945
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
173 KB
Volume
143-144
Category
Article
ISSN
0009-2797

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Nucleophilic substitution of protected 2
✍ Paola Ciapetti; AndrΓ© Mann; AngΓ¨le Shoenfelder; Maurizio Taddei πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 211 KB

The synthesis of a series of novel (t-amino acids based on the nucleophilic substitution of protected 2-amino-4-bromobutanoic acid (1) is described. Basic, acidic or neutral amino acids can be obtained; chimerical amino acids carrying a coenzyme type structure in the side chain, multifunctional amin