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Cotranslational Protein Integration into the ER Membrane Is Mediated by the Binding of Nascent Chains to Translocon Proteins

โœ Scribed by Peter J McCormick; Yiwei Miao; Yuanlong Shao; Jialing Lin; Arthur E Johnson


Book ID
117737206
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
414 KB
Volume
12
Category
Article
ISSN
1097-2765

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โœ Stephan Wahle; Wilhelm Stoffel ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 136 KB ๐Ÿ‘ 1 views

The four transmembrane domain topology of the proteolipid protein (PLP) in the myelin membrane of the central nervous system (CNS) has been further substantiated by biochemical studies. We have analyzed the cotranslational polytopic integration of nascent PLP during protein synthesis into the membra