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Corticotropin regulation of 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase in ovine adrenocortical cells: Inhibition by transforming growth factor β

✍ Scribed by Naville, Danielle; Rainey, William E.; Mason, J.Ian


Book ID
123594877
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
775 KB
Volume
75
Category
Article
ISSN
0303-7207

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Δ5-3β-hydroxysteroid dehydrogenase/Δ5-Δ4
✍ Stefanie Seidel; Wolfgang Kreis; Ernst Reinhard 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 380 KB

The in vitro transformation of pregnenolone into progesterone in Digitalis lanata tissues was shown to be catalyzed by a 3β-hydroxysteroid dehydrogenase/ketosteroid isomerase (3β-HSD). Product formation was monitored by HPLC. The enzyme could be partially characterized and 3β-HSD activities were mea