## Abstract Plasma exchange is the standard treatment for thrombotic thrombocytopenic purpura (TTP). For patients refractory to plasma exchange, treatment options are limited and often unsuccessful. The platelet thrombi that form in acquired TTP are believed to result from the presence of procoagul
Corticosteroids and rituximab as adjunctive treatments for thrombotic thrombocytopenic purpura
β Scribed by James N. George
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 708 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0361-8609
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π SIMILAR VOLUMES
Three patients (one with idiopathic thrombocytopenic purpura [ITP] and two with thrombotic thrombocytopenic purpura [TTP]) were treated with rituximab (anti-CD20 chimeric antibody) at a dose of 325 mg/m 2 administered weekly after they failed standard therapies. The patient with ITP who did not resp
## Abstract Thrombotic thrombocytopenic purpura (TTP) is a lifeβthreatening disease that is treated successfully with therapeutic plasma exchange (TPE) and often with corticosteroids; however, almost one third of TTP patients have treatment failures that require either longβterm TPEs or other adjun
## Abstract Ten patients with thrombocytopenia (TTP) were treated recently in our institution with plasma exchange (PE), steroids, and antiplatelet drugs. Additionally, fresh frozen plasma (FFP) was administered to nine patients, with folic acid given to eight patients. After 13 to 25 months of fo