Recently, we were led to re-examine our structural assignments of the final product reported in the above publication: further detailed analyses showed that the product obtained after amino group deprotection was actually L-4,4- difluoroglutamic acid 9 due to concomitant hydrolytic cleavage of the a
Corrigendum to “Towards the synthesis of (+)-discodermolide”: [Tetrahedron Lett. 42 (2001) 4713–4716]
✍ Scribed by J.S. Yadav; Sunny Abraham; M.Muralidhar Reddy; Gowravaram Sabitha; A.Ravi Sankar; A.C. Kunwar
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- French
- Weight
- 85 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
The authors regret that the structures of 14-17 in Scheme 3 have been drawn incorrectly. The corrected Scheme is shown below. Scheme 3. (a) LAH, THF, 0°C-rt, 4 h; (b) TBDPS-Cl, imidazole, DCM, 0°C-rt, 2 h; (c) DEAD, TPP, p-NO 2 C 6 H 4 -COOH, THF, 0°C-rt; (d) Dess-Martin periodinane, DCM, rt, 2 h; (e) NaBH 4 , MeOH/THF, 0°C-rt, 1 h; (f) TBAF, THF, rt, 1.5 h; (g) IBX, DMSO/DCM, rt, 6 h; (h) NaCNBH 3 , MeOH/AcOH, pH 5.5, rt, 1 h; (i) TBDMS-Cl, imidazole, DCM, 0°C-rt, 1.5 h; (j) 1% NaOH, THF, 3 h, H + , CH 3 COONa, Ac 2 O, warm, 5 min.
📜 SIMILAR VOLUMES
In Table 1, p. 7926, entries 13, 14, and 15 in the catalyst column should read as follows: 13 Pd(P t Bu 2 (OH)) 2 Cl 2 14 Pd(P t Bu 2 (OH)) 2 Cl 2 15 Pd(P t Bu 2 (OH)) 2 Cl 2 Also on p. 7928 the Acknowledgement section should read as follows: We thank Dr. George Y. Li (DuPont Central Research and Co
Footnote 5 of the above Tetrahedron Letter states that ''The spontaneous rearrangement of Sch. 49028 into phomactin A was observed by Pattenden et al. during their synthesis, see ref. 4. 1 '' However, it should be made absolutely clear that Goldring and Pattenden did not state in their paper 1 that