Highly effective and enantioselective Ph
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Lin Peng; Liang-Liang Wang; Jian-Fei Bai; Li-Na Jia; Qing-Chuan Yang; Qing-Chun
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Article
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2011
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Elsevier Science
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French
⚖ 413 KB
Cinchona alkaloids were first successfully reported to promote enantioselective Phospho-Aldol reaction of diphenyl phosphite to a variety of N-alkylated isatin derivatives in good to excellent yields (up to 99%) and moderate to good enantioselectivities (up to 73% ee) almost in no time.