High-Density DNA Functionalization by a
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Katrin Gutsmiedl; Danila Fazio; Thomas Carell
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Article
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2010
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John Wiley and Sons
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English
β 454 KB
π 2 views
## Abstract We report the regioselective Cuβfree click modification of styrene functionalized DNA with nitrile oxides. A series of modified oligodeoxynucleotides (nine base pairs) was prepared with increasing styrene density. 1,3βDipolar cycloaddition with nitrile oxides allows the high density fun