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Corrigendum: GilR, an Unusual Lactone-Forming Enzyme Involved in Gilvocarcin Biosynthesis

✍ Scribed by Madan Kumar Kharel; Pallab Pahari; Hui Lian; Jürgen Rohr


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
86 KB
Volume
11
Category
Article
ISSN
1439-4227

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GilR, an Unusual Lactone-Forming Enzyme
✍ Madan Kumar Kharel; Pallab Pahari; Hui Lian; Jürgen Rohr 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 193 KB

## Abstract **Last at last**: The terminal step of the gilvocarcin V (GV) biosynthetic pathway is an unusual lactone formation. Here we show that the enzyme, GilR, dehydrogenates the hemiacetal moiety of pregilvocarcin V to the lactone found in GV by using covalently bound FAD.magnified image