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Correlation of tissue and blood plasminogen activation system in breast cancer

✍ Scribed by Sun Young Rha; Woo Ick Yang; Soo Jung Gong; Jin Ju Kim; Nae Choon Yoo; Jae Kyung Roh; Jin Sik Min; Kyong Sik Lee; Byung Soo Kim; Hyun Cheol Chung

Book ID
117469729
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
136 KB
Volume
150
Category
Article
ISSN
0304-3835

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Urokinase plasminogen activator (uPA) is a serine protease involved in cancer invasion and metastasis. uPA mediates its action while attached to a membrane-bound receptor (uPAR). In this investigation we show that uPAR levels correlate with uPA levels in human breast cancers. uPAR levels, however, d