Correlation of antinuclear antibody and anti-double-stranded DNA antibody with clinical response to infliximab in patients with rheumatoid arthritis: a retrospective clinical study
✍ Scribed by Naoichiro Yukawa, Takao Fujii, Seiko Kondo-Ishikawa…
- Book ID
- 120706005
- Publisher
- BioMed Central
- Year
- 2011
- Tongue
- English
- Weight
- 330 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1478-6354
- DOI
- 10.1186/ar3546
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## Abstract ## Objective To investigate why the serum of a pediatric patient with systemic lupus erythematosus was persistently (>30 months) and strongly positive for antibodies to double‐stranded DNA (dsDNA) as revealed by enzyme‐linked immunosorbent assay (ELISA), but yielded negative results on
## Abstract ## Objective Treatment of patients with infliximab, a chimeric monoclonal IgG1 antibody against tumor necrosis factor, may result in the formation of infliximab‐specific IgG antibodies. This study evaluated the clinical significance of these antibodies in patients with rheumatoid arthr