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Clinical response, pharmacokinetics, development of human anti-chimaeric antibodies, and synovial tissue response to rituximab treatment in patients with rheumatoid arthritis

โœ Scribed by Thurlings, R M; Teng, O; Vos, K; Gerlag, D M; Aarden, L; Stapel, S O; van Laar, J M; Tak, P P; Wolbink, G J


Book ID
124160027
Publisher
BMJ Publishing Group
Year
2009
Tongue
English
Weight
354 KB
Volume
69
Category
Article
ISSN
0003-4967

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โœ Gerrit Jan Wolbink; Marijn Vis; Willem Lems; Alexandre E. Voskuyl; Els De Groot; ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 80 KB ๐Ÿ‘ 2 views

## Abstract ## Objective Treatment of patients with infliximab, a chimeric monoclonal IgG1 antibody against tumor necrosis factor, may result in the formation of infliximabโ€specific IgG antibodies. This study evaluated the clinical significance of these antibodies in patients with rheumatoid arthr