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Correlation between the pharmacokinetics and pharmacodynamics of dopamine in healthy subjects

✍ Scribed by U. Gundert-Remy; J. Penzien; R. Hildebrandt; W. Mäurer; E. Weber


Publisher
Springer
Year
1984
Tongue
English
Weight
617 KB
Volume
26
Category
Article
ISSN
0031-6970

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This study determined the kinetics of the effects of atropine on heart rate and saliva flow in three healthy male volunteers after intravenous administration of 1.35 and 2.15 mg of the drug. The pharmacokinetics of atropine and its primary metabolite, tropine, were determined simultaneously. Both th