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Correlation between the in vivo effects of some griseofulvin derivatives and their in vitro interactions with mammalian microtubules

✍ Scribed by Lluis Mir; Marie-Louise Oustrin; Pierre Lecointe; Michel Wright


Book ID
115908366
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
263 KB
Volume
88
Category
Article
ISSN
0014-5793

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✍ Akira Takada; Shahid Lodhi; Norman D. Weiner; Jochen Schacht πŸ“‚ Article πŸ“… 1982 πŸ› John Wiley and Sons 🌐 English βš– 207 KB

Low concentrations of poly-L-lysine, a polycationic hydrophilic molecule, caused a large expansion of polyphosphoinositide monolayers and produced a significant loss of cochlear microphonic potentials in perilymphatic perfusions in the guinea pig. In contrast, the monomeric L-lysine had only slight