Correlation between steady-state plasma concentrations of mianserin and trazodone in depressed patients
โ Scribed by K. Otani; G. Tybring; K. Mihara; N. Yasui; S. Kaneko; T. Ohkubo; T. Nagasaki; K. Sugawara
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 269 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0031-6970
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AMtracL This 6-week, double-blind, randomised parallel group study was carried out to assess the efficacy and tolerability of 150 mg trazodone nocte and 30-60 mg mianserin nocte in the treatment of depression in general practice. Special emphasis was placed on the effect of treatment on psychomotor
## Objective There are few data concerning a clear relationship between the clinical effect of paroxetine and plasma drug concentrations, although therapeutic ranges have been established for some tricyclic antidepressants. ## Methods In this study, 120 patients with major depressive disorders we