๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Correlation between pharmacokinetics and pharmacologic effects of a new imidazole thromboxane synthetase inhibitor

โœ Scribed by Toshio Iwata; Hiroshi Mikashima; Rikuo Takamatsu


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
676 KB
Volume
79
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Synthesis of tritium labelled 5,6-dihydr
โœ Erminia Fontana; Gian Piero Vicario ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 257 KB

## Abstract Synthesis of [^3^H]FCE 22178, namely 5,6โ€dihydroโ€7โ€(1Hโ€[Gโ€^3^H]imidazolโ€1โ€yl)โ€naphthaleneโ€2โ€carboxylic acid 5 was performed in three steps from 5,6,7,8โ€tetrahydroโ€8โ€hydroxyโ€7โ€(1Hโ€imidazolโ€1โ€yl)โ€naphtaleneโ€2โ€carboxylic acid 2 by bromination, catalytic tritiation and final dehydration, in

The effect of CV-4151, a selective inhib
โœ Tsunehiko Kuzuya; Yoshihiro Kimura; Shiro Hoshida; Kazuhisa Kodama; Nobuto Nakam ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer US ๐ŸŒ English โš– 585 KB

The pharmacokinetics and pharmacologic effects of a potent, selective inhibitor of thromboxane synthetase, CV-4151 [(E)-7-phenyl-7-(3-pyridyl)-6-heptenoic acid] on prostanoid formation and platelet aggregation were studied in 42 healthy male volunteers. The drug was well tolerated. After oral admini