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Correlation between mutations in the E2 region of HCV genotype 1 isolates and responsiveness to IFNα

✍ Scribed by T. Berg; A. Mas-Marques; M. Höhne; U. Hopf; B. Wiedenmann; E. Schreier

Book ID
119526042
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
148 KB
Volume
32
Category
Article
ISSN
0168-8278

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## Abstract Heterogeneity of subgenomic regions of hepatitis C virus (HCV) may be associated with response to interferon (IFN) therapy. The amino acid sequences of the PKR/eIF‐2α phosphorylation homology domain (pePHD), IFN sensitivity determining region (ISDR), PKR binding domain (PKRBD), and vari