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Correlation between CYP1A1 transcript, protein level, enzyme activity and DNA adduct formation in normal human mammary epithelial cell strains exposed to benzo[a]pyrene

✍ Scribed by Divi, R. L.; Einem Lindeman, T. L.; Shockley, M. E.; Keshava, C.; Weston, A.; Poirier, M. C.


Book ID
126920125
Publisher
Oxford University Press
Year
2014
Tongue
English
Weight
624 KB
Volume
29
Category
Article
ISSN
0267-8357

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## Abstract We hypothesized that chlorophyllin (CHLN) would reduce benzo[__a__]pyrene‐DNA (BP‐DNA) adduct levels. Using normal human mammary epithelial cells (NHMECs) exposed to 4 ΞΌM BP for 24 hr in the presence or absence of 5 ΞΌM CHLN, we measured BP‐DNA adducts by chemiluminescence immunoassay (C