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Correlation between centrosome abnormalities and chromosomal instability in human pancreatic cancer cells

✍ Scribed by Norihiro Sato; Kazuhiro Mizumoto; Masafumi Nakamura; Naoki Maehara; Yohji A Minamishima; Shoko Nishio; Eishi Nagai; Masao Tanaka


Book ID
114135007
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
283 KB
Volume
126
Category
Article
ISSN
0165-4608

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Measurement of the nuclear DNA content allows classification of human cancers as either diploid or aneuploid. To gain further insight into mechanisms of aneuploidy, we compared the cytogenetic profile of mismatch-repair-deficient diploid versus mismatch-repair-proficient aneuploid colorectal carcino