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AURKA amplification, chromosome instability, and centrosome abnormality in human pancreatic carcinoma cells

✍ Scribed by Jijiang Zhu; James L. Abbruzzese; Julie Izzo; Walter N. Hittelman; Donghui Li


Book ID
113512589
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
337 KB
Volume
159
Category
Article
ISSN
0165-4608

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Measurement of the nuclear DNA content allows classification of human cancers as either diploid or aneuploid. To gain further insight into mechanisms of aneuploidy, we compared the cytogenetic profile of mismatch-repair-deficient diploid versus mismatch-repair-proficient aneuploid colorectal carcino