𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Correlation between cardiac 123I-MIBG and odor identification in patients with Parkinson's disease and multiple system atrophy

✍ Scribed by Phil Hyu Lee; Seung Hyeon Yeo; Hyun Joon Kim; Hyo Young Youm

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
68 KB
Volume
21
Category
Article
ISSN
0885-3185

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

We investigated an association between olfaction and cardiac ^123^I‐metaiodobenzylguanidine (MIBG) uptake in patients with Parkinson's disease (PD) and multiple system atrophy (MSA). There was a significant positive correlation between cardiac MIBG uptake and the Cross‐Cultural Smell Identification (CCSI) score in patients with PD (r = 0.56; P = 0.003) independent of the disease duration or clinical rating of motor status. However, patients with MSA did not show a significant correlation between cardiac MIBG uptake and the CCSI score. Our findings suggest that the functional losses of the olfactory and cardiac sympathetic systems are closely coupled in PD. © 2006 Movement Disorder Society

📜 SIMILAR VOLUMES

Analysis of the relationship between mus
Analysis of the relationship between muscle sympathetic nerve activity and cardiac 123I-metaiodobenzylguanidine uptake in patients with Parkinson's disease
✍ Kazumasa Shindo; Eri Kaneko; Harue Watanabe; Tetsuhiko Sugimoto; Emiko Ohta; Ken 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 73 KB 👁 1 views

## Abstract To analyze the correlation between muscle sympathetic nerve activity (MSNA) and cardiac ^123^I‐metaiodobenzylguanidine (MIBG) uptake in patients with Parkinson's disease (PD), we measured both parameters in 14 PD patients who were 51 to 82 years of age (mean, 63.1 ± 8.7 years). The dura

Comparison of diffusion-weighted imaging
Comparison of diffusion-weighted imaging and [123I]IBZM-SPECT for the differentiation of patients with the Parkinson variant of multiple system atrophy from those with Parkinson's disease
✍ Klaus Seppi; Michael F.H. Schocke; Eveline Donnemiller; Regina Esterhammer; Chri 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 97 KB

## Abstract Both dopamine D2 receptor (D2R) binding single‐photon emission computed tomography (SPECT) with [^123^I]iodobenzamide (IBZM) and diffusion‐weighted imaging (DWI) have been shown to contribute to the differential diagnosis of patients with the Parkinson variant of multiple system atrophy

Brain-derived neurotrophic factor gene p
Brain-derived neurotrophic factor gene polymorphisms in Japanese patients with sporadic Alzheimer's disease, Parkinson's disease, and multiple system atrophy
✍ Masataka Nishimura; Sadako Kuno; Ryuji Kaji; Hideshi Kawakami 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 56 KB

## Abstract We studied two genetic polymorphisms (240C/T and 480G/A) of the brain‐derived neurotrophic factor (BDNF) gene in Japanese patients with Alzheimer's disease (AD, n = 172), Parkinson's disease (PD, n = 327), and multiple system atrophy (MSA, n = 122), as well as controls (n = 275). The di

Electromyography of the external anal sp
Electromyography of the external anal sphincter in patients with Parkinson's disease and multiple system atrophy: Frequency of abnormal spontaneous activity and polyphasic motor unit potentials
✍ Johannes Schwarz; Malte Kornhuber; Christian Bischoff; Andreas Straube 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 107 KB 👁 2 views

Electromyographic studies of the external anal sphincter muscle have received increasing attention in the differential diagnosis of patients with parkinsonism. Based on the fact that the external anal sphincter muscle is partly innervated by fibers that originate in Onuf's nucleus in the segments S2