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Correlation between autocrine aromatase activity and receptor status in receptor positive and receptor negative human breast cancer cell lines

โœ Scribed by P.J. Langecker; K.W. Possinger; A. Staebler; S. Scouropoulou; T.C. Lorenz; E. Doischer


Book ID
116006881
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
113 KB
Volume
28
Category
Article
ISSN
0022-4731

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## Abstract Recent studies demonstrate that abnormalities in PTEN may be one of the most frequent genetic events observed in human cancers. PTEN dysfunction leads to tumorigenesis through unopposed survival signals mediated __via__ activated protein kinase B (PKB), which may also be associated with