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Correlated abnormalities of transforming growth factor-β1 response and p53 expression in thyroid epithelial cell transformation

✍ Scribed by Wyllie, F.S.; Dawson, T.; Bond, J.A.; Goretzki, P.; Game, S.; Prime, S.; Wynford-Thomas, D.


Book ID
122763337
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
944 KB
Volume
76
Category
Article
ISSN
0303-7207

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✍ Ronald W. Steigerwalt; Joyce E. Rundhaug; Paul Nettesheim 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 925 KB

## Abstract The purpose of our studies was to define abnormalities in the transforming growth factor‐β (TGF‐β) system of transformed rat tracheal epithelial (RTE) cells that might cause their abnormal growth behavior. We found that many, but not all, of the transformed cell lines were hyporesponsiv