Correction: Virtual Combinatorial Libraries: Dynamic Generation of Molecular and Supramolecular Diversity by Self-Assembly

Generation of novel DNA-binding compound

Generation of novel DNA-binding compounds by selection and amplification from self-assembled combinatorial libraries

✍ Bryan Klekota; Mark H. Hammond; Benjamin L. Miller 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 282 KB

We describe a general method for the selection of compounds from self-assembled libraries which employs an immobilized receptor (i.e., an affinity reagent) to effect the selection. Using commercially available oligo d(A.T) DNA-cellulose resin, a set of three setereoisomeric coordination complexes ar