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Correction of Abnormal Retinal Pathways Found with Albinism by Introduction of a Functional Tyrosinase Gene in Transgenic Mice

✍ Scribed by Glen Jeffery; Günther Schütz; Lluı́s Montoliu

Book ID: 115597249
Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 549 KB
Volume: 166
Category: Article
ISSN: 0012-1606
DOI: 10.1006/dbio.1994.1329

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## Abstract Summary: Deletion of the tyrosinase locus control region (LCR) in transgenic mice results in variegated expression in the skin. Here we investigate the pigmentation pattern of other tissues that express tyrosinase: iris, choroid, and retina in the same animals. A mosaic distribution of