Correction for partial volume errors in MR heart perfusion imaging

✍ Scribed by Herbert Köstler; Christian Ritter; Martin Reiss-Zimmermann; Meinrad Beer; Dietbert Hahn; Jörn Sandstede

• Publisher: John Wiley and Sons
• Year: 2004
• Tongue: English
• Weight: 291 KB
• Volume: 51
• Category: Article
• ISSN: 0740-3194
• DOI: 10.1002/mrm.20015

✦ Synopsis

Abstract

Myocardial MR first‐pass perfusion time courses are contaminated by signals from the ventricles (spillover) as a consequence of partial volume effects and motion. An early increase in the signal intensity from the myocardium is an indicator of contamination. This contamination leads to under‐ or overestimation of perfusion, depending on the amount of contamination. In this work a simple method for contamination correction is proposed: curves proportional to the signal intensity time courses in the ventricles are subtracted from the signal intensity time courses in the myocardium to minimize the variance of signal before the arrival of the contrast medium in the myocardium. The proposed correction is easy to apply, removes the contamination, and leads to more precise perfusion values. Magn Reson Med 51:848–852, 2004. © 2004 Wiley‐Liss, Inc.