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Pitfalls in the Measurement of Metabolite Concentrations Using the One-Pulse Experiment in in Vivo NMR: Commentary on ‘On Neglecting Chemical Exchange Effects When Correcting in Vivo31P MRS Data for Partial Saturation,’: Volume 149, Number 2 (2001), pages 251–257

✍ Scribed by Richard G.S. Spencer; Kenneth W. Fishbein; Craig J. Galban

Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
19 KB
Volume
151
Category
Article
ISSN
1090-7807

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Pitfalls in the Measurement of Metabolit
Pitfalls in the Measurement of Metabolite Concentrations Using the One-Pulse Experiment in in Vivo NMR: Commentary on “On Neglecting Chemical Exchange Effects When Correcting in Vivo31P MRS Data for Partial Saturation”
✍ Richard G.S. Spencer; Kenneth W. Fishbein; Craig J. Galban 📂 Article 📅 2001 🏛 Elsevier Science 🌐 English ⚖ 75 KB

In an article in a previous issue of the Journal of Magnetic Resonance, Ouwerkerk and Bottomley (J. Magn. Reson. 148, pp. 425--435, 2001) show that even in the presence of chemical exchange, the dependence of saturation factors on repetition time in the one-pulse experiment is approximately monoexpo

On Neglecting Chemical Exchange When Cor
On Neglecting Chemical Exchange When Correcting in Vivo31P MRS Data for Partial Saturation: Commentary on: “Pitfalls in the Measurement of Metabolite Concentrations Using the One-Pulse Experiment in in Vivo NMR”
✍ Ronald Ouwerkerk; Paul A. Bottomley 📂 Article 📅 2001 🏛 Elsevier Science 🌐 English ⚖ 154 KB

This article replies to Spencer et al. (J. Magn. Reson. 149, 251--257, 2001) concerning the degree to which chemical exchange affects partial saturation corrections using saturation factors. Considering the important case of in vivo (31)P NMR, we employ differential analysis to demonstrate a broad r