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Coronavirus Translational Regulation: Leader Affects mRNA Efficiency

✍ Scribed by Stanley M. Tahara; Therese A. Dietlin; Cornelia C. Bergmann; Gary W. Nelson; Shigeru Kyuwa; Richard P. Anthony; Stephen A. Stohlman

Book ID
112269847
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
721 KB
Volume
202
Category
Article
ISSN
0042-6822

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Synthetic oligonucleotides encoding the 5'non-translated (leader) sequence of the coat protein mRNA of alfalfa mosaic virus RNA 4 or the f~' leader sequence of tobacco mosaic virus RNA were used to replace the natural leader region of the yeast phosphoglycerate kinase (PGK1) mRNAs and the translatio