Over the past few years, we have witnessed exciting advances in protein design. Several groups have reported success in the design of hydrophobic cores, and the principles developed in these studies have been recently applied to the full sequence design of a small protein motif and the design of a c
โฆ LIBER โฆ
Core-packing constraints, hydrophobicity and protein design
โ Scribed by Enoch P Baldwin; Brian W Matthews
- Book ID
- 103978643
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 767 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0958-1669
No coin nor oath required. For personal study only.
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## Abstract We present a novel method called RosettaHoles for visual and quantitative assessment of underpacking in the protein core. RosettaHoles generates a set of spherical cavity balls that fill the empty volume between atoms in the protein interior. For visualization, the cavity balls are aggr
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