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Copy number variants (CNVs) in primate species using array-based comparative genomic hybridization

✍ Scribed by Ömer Gökçümen; Charles Lee

Book ID
116987086
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
690 KB
Volume
49
Category
Article
ISSN
1046-2023

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Genomic copy-number variations (CNVs) involving large DNA segments are known to cause many genetic disorders. Depending on the changes, they are predicted to lead either to decreased or an increased gene expression. However, the ability to detect smaller exonic copy-number changes has not been explo