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Genome-wide discovery of chromosomal copy number variants in human amniotic cell using array-based comparative genomic hybridization

✍ Scribed by Sang Min Lee; Young Rok Seo; Min Hyung Jung


Book ID
107693768
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
494 KB
Volume
7
Category
Article
ISSN
1738-642X

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Detection of exonic copy-number changes
✍ Yoann Saillour; Mireille CossΓ©e; France Leturcq; AurΓ©lie Vasson; Caroline Beugne πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 517 KB

Genomic copy-number variations (CNVs) involving large DNA segments are known to cause many genetic disorders. Depending on the changes, they are predicted to lead either to decreased or an increased gene expression. However, the ability to detect smaller exonic copy-number changes has not been explo