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Coprescription of Tamoxifen and Medications That Inhibit CYP2D6

✍ Scribed by Sideras, K.; Ingle, J. N.; Ames, M. M.; Loprinzi, C. L.; Mrazek, D. P.; Black, J. L.; Weinshilboum, R. M.; Hawse, J. R.; Spelsberg, T. C.; Goetz, M. P.

Book ID
126475936
Publisher
American Society of Clinical Oncology
Year
2010
Tongue
English
Weight
270 KB
Volume
28
Category
Article
ISSN
0732-183X

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The cytochrome P450 2D6 (CYP2D6) is an enzyme known to metabolize a variety of xenobiotics and drugs. Inter-individual variation in the metabolic capacity of this enzyme has been extensively studied and associations with genotype have been established. Genetic polymorphisms have been grouped as nonf