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Copper(II) complexes of (1-[isopropylamine]-3-[1-naphthyloxy]-2-propanol) (propranolol)

✍ Scribed by Panayot R. Bontchev; Hussein Kadum; Bissera Evtimova; Chudomir Nachev; Darvin Ivanov; Ekaterina Zhecheva; Dimiter Mehandjiev


Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
559 KB
Volume
48
Category
Article
ISSN
0162-0134

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Kinetic resolution of 1-chloro-3-(1-naph
✍ M Kapoor; N Anand; S Koul; S.S Chimni; K.S Manhas; C Raina; R Parshad; S.C Tanej πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 English βš– 172 KB

(R)- and (S)-1-chloro-3-(1-naphthyloxy)-2-propanol are intermediates in the synthesis of beta-adrenergic blocking agents and antihypertensive drugs such as propranolol and nadoxolol. Herein, improvement in the preparation of racemic 1-chloro-3-(1-naphthyloxy)-2-propanol generated from 1-naphthol and