Copper(II)-Bisoxazoline-Catalysed Asymmetric Diels−Alder Reactions of α-Thioacrylates
✍ Scribed by Varinder K. Aggarwal; D. Elfyn Jones; Ana M. Martin-Castro
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 308 KB
- Volume
- 2000
- Category
- Article
- ISSN
- 1434-193X
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Catalytic Asymmetric Diels-Alder Reactions of α-Thioacrylates for the Preparation of Norbornenone. -Cu(II)-catalyzed asymmetric Diels-Alder cycloaddition of α-thioacrylates (I) with excess cyclopentadiene using a bisoxazoline as chiral auxiliary provides the corresponding cycloadducts (III) in high
## Abstract Highly enantioselective Diels–Alder (DA) and inverse‐electron‐demand hetero‐Diels–Alder (HDA) reactions of β,γ‐unsaturated α‐ketoesters with cyclopentadiene catalyzed by chiral __N__,__N′__‐dioxide–Cu(OTf)~2~ (Tf=triflate) complexes have been developed. Quantitative conversion of β,γ‐un
## Abstract For Abstract see ChemInform Abstract in Full Text.