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Copper(I)-picolinic acid catalyzed N-arylation of hydrazides

✍ Scribed by Miu Suen Lam; Hang Wai Lee; Albert S.C. Chan; Fuk Yee Kwong

Book ID
104095749
Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
185 KB
Volume
49
Category
Article
ISSN
0040-4039

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✦ Synopsis

An efficient copper-catalyzed carbon-nitrogen bond formation is described. The copper(I) complex with commercially available 2-picolinic acid ligand was found to be effective in N-arylation of N-Boc-hydrazine. This methodology offers a regioselective N-arylation of hydrazides using a variety of substituted aryl iodides.

πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: Copper(I)/Picolinic
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✍ Miu Suen Lam; Hang Wai Lee; Albert S. C. Chan; Fuk Yee Kwong πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons βš– 27 KB

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