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Copper-catalyzed asymmetric conjugate addition of diethylzinc to substituted chalcones using a chiral phosphine ligand

✍ Scribed by Özdemir Dogan; Adnan Bulut; Savaş Polat; M. Ali Tecimer


Book ID
113929557
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
315 KB
Volume
22
Category
Article
ISSN
0957-4166

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Copper-catalyzed enantioselective conjug
✍ Manfred T. Reetz; Andreas Gosberg; Dominique Moulin 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 57 KB

BINOL-based diphosphonites in which ferrocene functions as the achiral backbone are excellent chiral ligands in the Cu(OTf) 2 -catalyzed conjugate addition of Et 2 Zn to enones, enantioselectivities of up to 99% being observed.