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Copper-Catalyzed Asymmetric Allylic Substitution of Allyl Phosphates with Aryl- and Alkenylboronates

✍ Scribed by Dr. Ryo Shintani; Dr. Keishi Takatsu; Momotaro Takeda; Prof. Dr. Tamio Hayashi


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
291 KB
Volume
50
Category
Article
ISSN
0044-8249

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Copper-catalyzed asymmetric allylic alkylation is an efficient C À C bond-forming reaction for obtaining optically active compounds. [1] The use of hard alkyl nucleophiles such as Grignard or organozinc reagents usually produces S N 2' products (g products) with excellent regio-and enantioselectivit