Efficient Chiral N-Heterocyclic Carbene/
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Khalid B. Selim; Yasumasa Matsumoto; Ken-ichi Yamada; Kiyoshi Tomioka
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Article
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2009
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John Wiley and Sons
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English
⚖ 304 KB
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Copper-catalyzed asymmetric allylic alkylation is an efficient C À C bond-forming reaction for obtaining optically active compounds. [1] The use of hard alkyl nucleophiles such as Grignard or organozinc reagents usually produces S N 2' products (g products) with excellent regio-and enantioselectivit