Copper Binding to the Neurotoxic Peptide
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Barbara Belosi; Elena Gaggelli; Remo Guerrini; Henryk Kozłowski; Marek Łuczkowsk
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Article
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2004
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John Wiley and Sons
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English
⚖ 242 KB
## Abstract __The human prion protein fragment PrP__~__106–126__~ __is a highly fibrillogenic peptide, resistant to proteinases and toxic to neurons; it derives from the normal prion protein (PrP__^__C__^__), with which it can interact, thus inhibiting its superoxide dismutase‐like activity. The sa