✦ LIBER ✦

Coordinated Roles of Pregnane X Receptor and Constitutive Androstane Receptor in Autoinduction of Voriconazole Metabolism in Mice

✍ Scribed by Ohbuchi, M.; Yoshinari, K.; Kaneko, H.; Matsumoto, S.; Inoue, A.; Kawamura, A.; Usui, T.; Yamazoe, Y.

Book ID: 118221445
Publisher: American Society for Microbiology
Year: 2012
Tongue: English
Weight: 1004 KB
Volume: 57
Category: Article
ISSN: 0066-4804
DOI: 10.1128/aac.01900-12

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Coordinate regulation of human drug-meta

Coordinate regulation of human drug-metabolizing enzymes, and conjugate transporters by the Ah receptor, pregnane X receptor and constitutive androstane receptor

✍ Christoph Köhle; Karl Walter Bock 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 389 KB

Dual role of orphan nuclear receptor pre

Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice

✍ Simrat P. S. Saini; Ying Mu; Haibiao Gong; David Toma; Hirdesh Uppal; Songrong R 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 322 KB

The pregnane X receptor (PXR) and the constitutive androstane receptor (CAR) are implicated in xenobiotic and endobiotic detoxification, including the clearance of toxic bilirubin. Previous studies have suggested both overlapping and preferential regulation of target genes by these receptors, but th

Zearalenone activates pregnane X recepto

Zearalenone activates pregnane X receptor, constitutive androstane receptor and aryl hydrocarbon receptor and corresponding phase I target genes mRNA in primary cultures of human hepatocytes

✍ Imen Ayed-Boussema; Jean Marc Pascussi; Patrick Maurel; Hassen Bacha; Wafa Hasse 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 480 KB

Transactivation of ABCG2 through a novel

Transactivation of ABCG2 through a novel cis-element in the distal promoter by constitutive androstane receptor but not pregnane X receptor in human hepatocytes

✍ Satoshi Benoki; Kouichi Yoshinari; Tsubasa Chikada; Jun Imai; Yasushi Yamazoe 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 865 KB

Bioactive Terpenoids and Flavonoids from

Bioactive Terpenoids and Flavonoids from Ginkgo Biloba Extract Induce the Expression of Hepatic Drug-Metabolizing Enzymes Through Pregnane X Receptor, Constitutive Androstane Receptor, and Aryl hydrocarbon Receptor-Mediated Pathways

✍ Linhao Li; Joseph D. Stanton; Antonia H. Tolson; Yuan Luo; Hongbing Wang 📂 Article 📅 2008 🏛 Springer US 🌐 English ⚖ 232 KB

The Role of Constitutive Androstane Rece

The Role of Constitutive Androstane Receptor in Oxazaphosphorine-Mediated Induction of Drug-Metabolizing Enzymes in Human Hepatocytes

✍ Duan Wang; Linhao Li; Jennifer Fuhrman; Stephen Ferguson; Hongbing Wang 📂 Article 📅 2011 🏛 Springer US 🌐 English ⚖ 618 KB