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Coordinated fibroblast growth factor and heparan sulfate regulation of osteogenesis

✍ Scribed by Rebecca A. Jackson; Victor Nurcombe; Simon M. Cool

Book ID
116507563
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
476 KB
Volume
379
Category
Article
ISSN
0378-1119

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Heparan sulfate proteoglycans (HSPGs) are ubiquitous macromolecules associated with the cell surface and extracellular matrix (ECM) of a wide range of cells of vertebrate and invertebrate tissues [1,2]. The basic HSPG structure consists of a protein core to which several linear heparan sulfate (HS)