BalbIc3T3 cells in crowded cultures detach from the dish when deprived of serum, and the survivors incorporate 3H-thymidine a t a reduced rate. The detachment becomes pronounced two hours after removal of serum, and reaches its maximum rate between two and four hours. Cells in sparse cul-
Coordinate control of cytoskeletal remodeling and calcium mobilization during T-cell activation
β Scribed by Babich, Alexander; Burkhardt, Janis K.
- Book ID
- 121801469
- Publisher
- John Wiley and Sons
- Year
- 2013
- Tongue
- English
- Weight
- 367 KB
- Volume
- 256
- Category
- Article
- ISSN
- 0105-2896
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The physiological role of IP 3 -dependent Ca 2Ο© release in T cell activation was in question due to the contradictory findings that [8-(Diethylamino)octyl-3,4,5-trimethoxybenzoate, HCl] (TMB-8), an inhibitor of intracellular Ca 2Ο© mobilization, blocked T cell proliferation, curtailing specifically t