## Abstract Much controversy regarding the relationship between nutrients and serum in regulation of cell growth can be reconciled by recognizing that serum contains multiple factors which regulate different events in the cell cycle. Serum was fractioned into a platelet‐derived growth factor (PDGF)
Coordinate control of balb/c3T3 cell survival and multiplication by serum or calcium pyrophosphate complexes
✍ Scribed by A. Harry Rubin; Daniel F. Bowen-Pope
- Book ID
- 102882139
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 1009 KB
- Volume
- 98
- Category
- Article
- ISSN
- 0021-9541
No coin nor oath required. For personal study only.
✦ Synopsis
BalbIc3T3 cells in crowded cultures detach from the dish when deprived of serum, and the survivors incorporate 3H-thymidine a t a reduced rate. The detachment becomes pronounced two hours after removal of serum, and reaches its maximum rate between two and four hours. Cells in sparse cul-
📜 SIMILAR VOLUMES
## Abstract Platelet‐derived growth factor (PDGF) and platelet‐poor plasma, which lacks PDGF, both induce a rapid increase in the rate of total protein synthesis within quiescent, density‐arrested Balb/c‐3T3 cells. This stimulation of protein synthesis is associated with an increased aggregation of
## Abstract Membranes isolated from subconfluent cultures of Balb/c 3T3 cells have low energy‐dependent calcium uptake activity. Replating confluent cells at low density results in a prompt fall of energy‐dependent calcium uptake by membrane fractions. The level to which uptake activity falls is a