Conversion of α,β-unsaturated ketones into α-hydroxy ketones using an MnIII catalyst, phenylsilane and dioxygen: acceleration of conjugate hydride reduction by dioxygen
✍ Scribed by Philip Magnus; Andrew H Payne; Michael J Waring; David A Scott; Vince Lynch
- Book ID
- 104211274
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 111 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Treatment of a variety of a,b-unsaturated ketones with Mn(dpm) 3 (3 mol%)/PhSiH 3 (1.3 equiv.)/ isopropyl alcohol/O 2 , followed by reductive work-up with P(OEt) 3 resulted in the formation of a-hydroxyketones.
📜 SIMILAR VOLUMES
Treatment of a variety of a,b-unsaturated ketones with Mn(dpm) 3 (3 mol%)/PhSiH 3 (1.3 equiv.)/isopropyl alcohol with the exclusion of air resulted in the formation of the saturated ketone.
Treatment of a,b-unsaturated nitriles with Mn(dpm) 3 (3 mol%), PhSiH 3 in isopropyl alcohol in the presence of oxygen resulted in reduction and aand b-hydroxylation.