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Conversion of uridine into 2′-O-(2-methoxyethyl)uridine and 2′-O-(2-methoxyethyl)cytidine

✍ Scribed by Urtzi Legorburu; Colin B Reese; Quanlai Song

Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
332 KB
Volume
55
Category
Article
ISSN
0040-4020

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✦ Synopsis

Reaction between aluminium 2-methoxyethoxide and 2,2'-anhydro-1-fl-D-arabinofuranosyluracil 6 gives 2'-O-(2-methoxyethyl)uridine 9 in high yield. Compound 9 is converted into 2'-O-(2-methoxyethyl)cytidine 11 in good yield.

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