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Conversion of sandaracopimaric acid into an androstane analog steroid

✍ Scribed by Abad, A.; Agullo, C.; Arno, M.; Domingo, L. R.; Zaragoza, R. J.


Book ID
126259699
Publisher
American Chemical Society
Year
1990
Tongue
English
Weight
765 KB
Volume
55
Category
Article
ISSN
0022-3263

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Conversion of amino acids and dipeptides
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Acylamino carboxylic acids were degradated by the Hunsdiecker-reaction; the bromo-derivatives were reacted with NaPO(OQH5)z. Aminophosphonic acids were obtained by acidic hydrolysis, and half-blocked derivatives by the selective removal of masking substituents. Two phosphonopeptides [e.g. Alafosfali